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It affects at least 65 cellular pathways throughout the body, including: Serotonin receptors such as 5HT-1a, which are responsible for anxiety3 Vanilloid receptors such TRPV1, which are responsible for pain perception4 G-protein-coupled receptors (GPCRs), or membrane proteins responsible for moderating hormones and neurotransmitters5 Voltage-gated ion channels, which manage whether a neuron will send a signal6 Endorphins and opioid receptors For more information about CBD in general, check out our beginner’s guide to CBD